Ken Griffin acquired 2.27M Astrazeneca plc shares worth $186M. That's 0.16% of their equity portfolio (137th largest holding). The first Astrazeneca plc trade was made in Q2 2013. Since then Ken Griffin bought shares 61 more times and sold shares on 56 occasions. The stake costed the investor $142M, netting the investor a gain of 31% so far.